Argonne National Laboratory and Chain Reaction Innovations have strong ties to local and national innovation ecosystems. These affiliations with leading incubators, accelerators, business schools and STEM networks keep CRI abreast of market trends and engaged in forefront entrepreneurship activities. If you have interest in becoming an affiliate of CRI, please contact Janelle Richmond at


mHUB's members create breakthrough products in robotics, connected devices, sensors, energy tech, medical devices, smart building / cities, unmanned vehicles, and other cutting- edge innovations. By providing the right resources, mentorship, and access to manufacturing industry insiders, mHUB helps early-stage innovators go from prototype to product to sustainable business, driving a greater likelihood of success.

View More

Chicago Council on Science & Technology

The Chicago Council on Science and Technology's mission is to enhance the public’s understanding and appreciation of science and technology and their impact on society. C²ST partners with over 80 regional and national organizations. C²ST is an anchor to catalyze a more robust marketplace for science and gain more visibility for Chicago as a center of innovation and technology.

View More

Clean Energy Trust

CET is a non-profit cleantech accelerator to launch, fund and grow startups. Technology commercialization and mentorship, policy and advocacy programming, and supporting breakthrough clean energy research are the pillars of CET's mission.

Clean Energy Trust in a partnership withFreshwater Advisors, and with support from consulting partners Accenture, Deloitte, and EY. E, executes The Cleantech Innovation Bridge. CIB matches clean energy researchers and early-stage ventures with corporations seeking innovative energy technologies and solutions. The program is accelerating the pace of clean energy innovation in the Midwest region and beyond through real business opportunities between corporations and startups.

View More

Cleantech Open Midwest

Cleantech Open Midwest is the oldest and largest cleantech startup accelerator program, with the mission to find, fund, and foster entrepreneurs with ideas to solve our greatest environmental and energy challenges.

View More

Energy Foundry

Energy Foundry invests venture capital in today’s most promising energy innovators, and we work with the world’s leading energy companies to build and scale new ventures.

View More


We deliver an immersive education that teaches researchers how to successfully transfer knowledge into products and processes. It’s not about how to write a research paper, business plan, or NSF proposal. We empower teams of scientists, engineers, and researchers to understand the potential value of their technology and inventions, by teaching them how to assess the market opportunity for new technology and commercial potential:

View More


MATTER is a community of healthcare innovators, an incubator of ideas, and a catalyst for change. We are boots-on-the-ground entrepreneurs.

View More


PROPEL is a group of programs aimed at increasing the number and success rates of life sciences startups in Illinois.

View More

University of Chicago

The University of Chicago operates the Polsky Center for Entrepreneurship and Innovation, which unites the former Chicago Innovation Exchange, UChicago Tech and Polsky Center.

View More